I went to the gyn this week (twice) to see if I might have the vulvodynia or vestibulitis. The nurse practionier I see is so sweet but she admitted she knew little about those problems and sent me to the female doctor on staff. She feels I am in full blow menopause (even though I'm only 46 due to two different fsh levels tests that showed high levels of something or other. Anyway, she thinks I just have vaginal atrophy and gave me some samples and a script for estrace vaginal cream 0.1%. I am scared to try it for fear of side affects (and all the nasty stuff in the insert literature). She told me hardly any is absorbed systemically but I've read things on the net to the contrary. I see a few of you use it or have used it..any real problems? I'm more worried than anything about a blood clot or something. I have severe fibroymyalgia so I have weird sensations in my body anyway. I'm thinking maybe it's not worth trying it..what should I do? Please respond asap...I really obsess about these types of things. Thank you so much...and God bless..