Hi. I started using Estrace cream again after some urinary problems, and I noticed, once again, that my breasts got sore and I had a slight discharge. Has anyone noticed this too, and will this go away as my body gets used to it?

Thanks,
Meryl

Okay. I called the doctor's office today and found out that even though Estrace cream is not supposed to be systemic, it actually does get into your system and can cause breast tenderness and discharge. Thought some of you might want to know.