QUOTE (TidalWaves @ Sep 17 2009, 10:09 AM)

Thank you all so much for the help and the info!
I was not able to do the research for myself yesterday, just because of the emotional crisis I had been in.
I sure could have used the Ativan, but I ended up not taking it.
Didn't want to chance it being in my system for an extended period of time.
Maybe I will take some over the weekend, just so I can destress after this crazy week.
Thanks again!
Hey Bev,
I looked this up for you. Hope it helps a little.
Studies in healthy volunteers show that in single high doses Ativan (lorazepam) has a tranquilizing action on the central nervous system with no appreciable effect on the respiratory or cardiovascular systems.
Ativan (lorazepam) is readily absorbed with an absolute bioavailability of 90 percent. Peak concentrations in plasma occur approximately 2 hours following administration. The peak plasma level of lorazepam from a 2 mg dose is approximately 20 ng/mL.
The mean half-life of unconjugated lorazepam in human plasma is about 12 hours and for its major metabolite, lorazepam glucuronide, about 18 hours. At clinically relevant concentrations, lorazepam is approximately 85% bound to plasma proteins. Ativan (lorazepam) is rapidly conjugated at its 3-hydroxy group into lorazepam glucuronide which is then excreted in the urine. Lorazepam glu-curonide has no demonstrable CNS activity in animals.
The plasma levels of lorazepam are proportional to the dose given. There is no evidence of accumulation of lorazepam on administration up to six months.
Studies comparing young and elderly subjects have shown that advancing