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Megopause
Hi,

Would you please help me try to figure this out? I had my blood work done on cycle day 20.
Here are my results:
Free T4: 0.9
Free T3: 253
TSH 3rd generation 2.66
Thyroglobulin antibodies <20
Thyroid Peroxidase antibodies <10
Estradiol: 92
Progesterone: 18
Estrone: 70

It also states that something in my blood count is low , the MCHC is 31.8 (anemia?)

And my bilirubin is a bit high...

Bleh, I feel like crud today, it is cycle day 10 and I am a mess of anxiety, panic, dizzy, rapid heartbeat, I didn't sleep last night, I feel like I am going to throw up...God please can't this just stop?!

So do I need Estradiol or Progesterone? (when I tired the progesterone it made me feel bad I thought)

Please help and thanks so much!!
Meg
Floater
QUOTE (Megopause @ Jul 22 2009, 05:32 PM) *
Hi,

Would you please help me try to figure this out? I had my blood work done on cycle day 20.
Here are my results:
Free T4: 0.9
Free T3: 253
TSH 3rd generation 2.66
Thyroglobulin antibodies <20
Thyroid Peroxidase antibodies <10
Estradiol: 92
Progesterone: 18
Estrone: 70

It also states that something in my blood count is low , the MCHC is 31.8 (anemia?)

And my bilirubin is a bit high...

Bleh, I feel like crud today, it is cycle day 10 and I am a mess of anxiety, panic, dizzy, rapid heartbeat, I didn't sleep last night, I feel like I am going to throw up...God please can't this just stop?!

So do I need Estradiol or Progesterone? (when I tired the progesterone it made me feel bad I thought)

Please help and thanks so much!!
Meg


It would be very helpful if you could also put the labs ranges for "normal" as all labs are slightly different, and some members (like me) are Canadian and our numbers are completely different than US numbers.

Also, not sure where you are in the peri journey, but at the beginning P will often help alone...but as you get a little further into peri your E starts to drop off and supplementing P can make you feel worse unless you also use the E to balance it.
nc53215
i know my proges. was .49 and dr gave me p-cream in bio form, said i was low . compared to your 18 that is.... you sound normal in that dept, but i dont know... good luck hope you feel better soon
Megopause
Oh yes, sorry the normal ranges are now on here too, thanks.

QUOTE (Megopause @ Jul 22 2009, 06:32 PM) *
Hi,

Would you please help me try to figure this out? I had my blood work done on cycle day 20.
Here are my results:
Free T4: 0.9 (normal range: 0.8-1.8)
Free T3: 253 (normal range: 230-420)
So I guess I am in the normal range but on the low end of normal for those two Thyroid tests, I don't know what the normal ranges are for the rest, it is not listed on my paper.
TSH 3rd generation 2.66
Thyroglobulin antibodies <20
Thyroid Peroxidase antibodies <10
Estradiol: 92
Progesterone: 18
Estrone: 70

It also states that something in my blood count is low , the MCHC is 31.8 (anemia?)

And my bilirubin is a bit high...

Bleh, I feel like crud today, it is cycle day 10 and I am a mess of anxiety, panic, dizzy, rapid heartbeat, I didn't sleep last night, I feel like I am going to throw up...God please can't this just stop?!

So do I need Estradiol or Progesterone? (when I tired the progesterone it made me feel bad I thought)

Please help and thanks so much!!
Meg

Megopause

Also, not sure where you are in the peri journey, but at the beginning P will often help alone...but as you get a little further into peri your E starts to drop off and supplementing P can make you feel worse unless you also use the E to balance it.
[/quote]

Thank you, I think this may be my situation because from what I have read the Progesterone should have helped but I felt my symptoms were more pronounced when I took the Progesterone pills.

Meg
Floater
QUOTE (Megopause @ Jul 22 2009, 05:54 PM) *
Oh yes, sorry the normal ranges are now on here too, thanks.


Meg, that dark green is almost impossible to read on the dark blue...I THINK the T3 range is 230 - 450??? Is that right??? If it IS, then your T3 is probably a wee bit low.

There are a couple of ladies on here that are quite good with the Thyroid numbers. Why don't you start a new thread under the thyroid forum and put your numbers up there.
Megopause
QUOTE (Floater @ Jul 22 2009, 08:29 PM) *
Meg, that dark green is almost impossible to read on the dark blue...I THINK the T3 range is 230 - 450??? Is that right??? If it IS, then your T3 is probably a wee bit low.

There are a couple of ladies on here that are quite good with the Thyroid numbers. Why don't you start a new thread under the thyroid forum and put your numbers up there.


I know I relized after I used the green that it was hard to see but I felt too crummy to change it, lol, sorry.
I was unaware of a thyroid forum, it is not on the 34 symptom list is it? How do I get there?

Thanks,
Meg
Becca233
Hey check out this link, it might give you some answers...

http://www.keratin.com/ab/ab012.shtml#04

Hope this helps...
Becca233
Here's a paste of what they had to say, there is also a chart on the link...

An explanation of test results for sex hormones in women

Testosterone - Testosterone levels should be fairly low in women as compared to men. It is possible for a woman to have no testosterone production and still be healthy other than perhaps a diminished sex drive. In healthy women the majority of testosterone production (up to 70%) is derived from the conversion of DHEAS and androstenedione by enzymes within the skin. The rest is secreted direct from the ovaries and adrenal glands. An excess of testosterone, above the normal range signals a potential problem. Most doctors would consider a level above 50 ng/dl to be somewhat elevated. Above 100 ng/dl of testosterone in women is symptomatic of some kind of hyperandrogenism. If the testosterone is over 200 ng/dl an ovarian ultrasound is used to look for any ovarian tumors. The higher the testosterone level the more risk of hirsutism or androgenetic alopecia if there is no corresponding rise in androgen antagonists (estrogens and SHBG).

Estrogens - Estrogens come in several shapes and sizes but the common one and the one usually tested for is estradiol (E2). Estradiol concentrations in women vary considerably depending on age and the stage of the reproductive cycle. The normal range may be anywhere between 50-700 picograms per milliliter. At the time of ovulation the range may be between 100-400 picograms per milliliter. Estrogens antagonize (cancel out) the actions of androgen hormones so more estrogen in effect reduces androgen hormone activity. As such, an estrogen level at the higher end of the normal range is preferable in terms of reducing susceptibility to androgenetic alopecia. Currently, there is much debate about how estrogens may directly act on hair follicles. Hair follicles do express estrogen receptors so the follicle are directly responsive to estrogen hormone molecules. However, there is confusion as to what estrogens do to the follicles - whether they stimulate or inhibit hair growth. There may be a different response depending on the estrogen type. Abnormally high estrogen levels on day 3 may indicate existence of a functional cyst or diminished ovarian reserve - however, there are no reports of hair loss in association with abnormally high estrogen levels so the risk of hair loss seems to be a minor one.

Dehydroepiandrosterone (DHEA) - Dehydroepiandrosterone sulfate (DHEAS) is the sulfated form of Dehydroepiandrosterone (DHEA). DHEA is a relatively unstable molecule and it mostly gets converted to DHEAS before circulating in the blood stream. For the purpose of understanding androgenetic alopecia, DHEA and DHEAS can be regarded as basically the same thing. If DHEAS is over 700 micrograms per deciliter, an MRI is ordered to rule out and adrenal tumor. If the DHEAS is between 500 - 700 micrograms per deciliter, then further endocrine testing is usually needed to rule out adrenal hyperfunction such as adrenal hyperplasia. An elevated DHEAS level may be improved through use of dexamethasone, prednisone, or insulin-sensitizing medications. DHEA can be converted into more potent androgen forms, ultimately it can be converted into dihydrotestosterone by enzymes in the hair follicles. As such, A high DHEA level potentially suggests an increased susceptibility to hirsutism or androgenetic alopecia if there is no corresponding rise in androgen antagonists.

Follicle Stimulating Hormone (FSH) - FSH is often used as a gauge of ovarian reserve. In general, under 6 is excellent, 6-9 is good, 9-10 fair, 10-13 diminished reserve, 13+ very hard to stimulate. In PCOS testing, the LH:FSH ratio may be used in the diagnosis. The ratio is usually close to 1:1, but if the LH is higher, it is one possible indication of PCOS. For healthy hair growth then, the ratio of FSH to LH should be roughly equal.

Luteinizing Hormone (LH) - A normal LH level is similar to FSH. An LH that is higher than FSH is one indication of PCOS.

Prolactin - Increased prolactin levels can interfere with ovulation. They may also indicate further testing (MRI) should be done to check for a pituitary tumor. Some women with PCOS and associated hair problems also have hyperprolactinemia.

Progesterone (P4) - An elevated level may indicate a reduced fertility. A progesterone test is done to confirm ovulation. When a follicle releases its egg, it becomes what is called a corpus luteum and produces progesterone. A level over 5 probably indicates some form of ovulation, but most doctors want to see a level over 10 on a natural cycle, and a level over 15 on a medicated cycle. There is no mid-luteal level that predicts pregnancy. Some say the progesterone test may be more accurate if done first thing in the morning after fasting.

Sex Hormone Binding Globulin (SHBG) - Increased androgen production often leads to lower SHBG. This is a potential problem in terms of hair growth as SHBG is an antagonist to testosterone. SHBG binds to testosterone and renders it inactive. Bound testosterone cannot interact with androgen receptors on cells so it has no impact on hair follicles. A reduced SHBG level suggests a possible increase in susceptibility to hirsutism or androgenetic alopecia. The more SHBG there is the better in terms of healthy hair growth.



--------------------------------------------------------------------------------
Ah, Thank God for Copy/Paste - ya think...
surreallife
QUOTE (Becca233 @ Jul 23 2009, 12:01 PM) *
Here's a paste of what they had to say, there is also a chart on the link...

An explanation of test results for sex hormones in women

Testosterone - Testosterone levels should be fairly low in women as compared to men. It is possible for a woman to have no testosterone production and still be healthy other than perhaps a diminished sex drive. In healthy women the majority of testosterone production (up to 70%) is derived from the conversion of DHEAS and androstenedione by enzymes within the skin. The rest is secreted direct from the ovaries and adrenal glands. An excess of testosterone, above the normal range signals a potential problem. Most doctors would consider a level above 50 ng/dl to be somewhat elevated. Above 100 ng/dl of testosterone in women is symptomatic of some kind of hyperandrogenism. If the testosterone is over 200 ng/dl an ovarian ultrasound is used to look for any ovarian tumors. The higher the testosterone level the more risk of hirsutism or androgenetic alopecia if there is no corresponding rise in androgen antagonists (estrogens and SHBG).

Estrogens - Estrogens come in several shapes and sizes but the common one and the one usually tested for is estradiol (E2). Estradiol concentrations in women vary considerably depending on age and the stage of the reproductive cycle. The normal range may be anywhere between 50-700 picograms per milliliter. At the time of ovulation the range may be between 100-400 picograms per milliliter. Estrogens antagonize (cancel out) the actions of androgen hormones so more estrogen in effect reduces androgen hormone activity. As such, an estrogen level at the higher end of the normal range is preferable in terms of reducing susceptibility to androgenetic alopecia. Currently, there is much debate about how estrogens may directly act on hair follicles. Hair follicles do express estrogen receptors so the follicle are directly responsive to estrogen hormone molecules. However, there is confusion as to what estrogens do to the follicles - whether they stimulate or inhibit hair growth. There may be a different response depending on the estrogen type. Abnormally high estrogen levels on day 3 may indicate existence of a functional cyst or diminished ovarian reserve - however, there are no reports of hair loss in association with abnormally high estrogen levels so the risk of hair loss seems to be a minor one.

Dehydroepiandrosterone (DHEA) - Dehydroepiandrosterone sulfate (DHEAS) is the sulfated form of Dehydroepiandrosterone (DHEA). DHEA is a relatively unstable molecule and it mostly gets converted to DHEAS before circulating in the blood stream. For the purpose of understanding androgenetic alopecia, DHEA and DHEAS can be regarded as basically the same thing. If DHEAS is over 700 micrograms per deciliter, an MRI is ordered to rule out and adrenal tumor. If the DHEAS is between 500 - 700 micrograms per deciliter, then further endocrine testing is usually needed to rule out adrenal hyperfunction such as adrenal hyperplasia. An elevated DHEAS level may be improved through use of dexamethasone, prednisone, or insulin-sensitizing medications. DHEA can be converted into more potent androgen forms, ultimately it can be converted into dihydrotestosterone by enzymes in the hair follicles. As such, A high DHEA level potentially suggests an increased susceptibility to hirsutism or androgenetic alopecia if there is no corresponding rise in androgen antagonists.

Follicle Stimulating Hormone (FSH) - FSH is often used as a gauge of ovarian reserve. In general, under 6 is excellent, 6-9 is good, 9-10 fair, 10-13 diminished reserve, 13+ very hard to stimulate. In PCOS testing, the LH:FSH ratio may be used in the diagnosis. The ratio is usually close to 1:1, but if the LH is higher, it is one possible indication of PCOS. For healthy hair growth then, the ratio of FSH to LH should be roughly equal.

Luteinizing Hormone (LH) - A normal LH level is similar to FSH. An LH that is higher than FSH is one indication of PCOS.

Prolactin - Increased prolactin levels can interfere with ovulation. They may also indicate further testing (MRI) should be done to check for a pituitary tumor. Some women with PCOS and associated hair problems also have hyperprolactinemia.

Progesterone (P4) - An elevated level may indicate a reduced fertility. A progesterone test is done to confirm ovulation. When a follicle releases its egg, it becomes what is called a corpus luteum and produces progesterone. A level over 5 probably indicates some form of ovulation, but most doctors want to see a level over 10 on a natural cycle, and a level over 15 on a medicated cycle. There is no mid-luteal level that predicts pregnancy. Some say the progesterone test may be more accurate if done first thing in the morning after fasting.

Sex Hormone Binding Globulin (SHBG) - Increased androgen production often leads to lower SHBG. This is a potential problem in terms of hair growth as SHBG is an antagonist to testosterone. SHBG binds to testosterone and renders it inactive. Bound testosterone cannot interact with androgen receptors on cells so it has no impact on hair follicles. A reduced SHBG level suggests a possible increase in susceptibility to hirsutism or androgenetic alopecia. The more SHBG there is the better in terms of healthy hair growth.



--------------------------------------------------------------------------------
Ah, Thank God for Copy/Paste - ya think...



Out of all this which is the cuprit for facial hair and acne? Anyone know?
Megopause
QUOTE (Becca233 @ Jul 23 2009, 11:01 AM) *
Here's a paste of what they had to say, there is also a chart on the link...

An explanation of test results for sex hormones in women

Testosterone - Testosterone levels should be fairly low in women as compared to men. It is possible for a woman to have no testosterone production and still be healthy other than perhaps a diminished sex drive. In healthy women the majority of testosterone production (up to 70%) is derived from the conversion of DHEAS and androstenedione by enzymes within the skin. The rest is secreted direct from the ovaries and adrenal glands. An excess of testosterone, above the normal range signals a potential problem. Most doctors would consider a level above 50 ng/dl to be somewhat elevated. Above 100 ng/dl of testosterone in women is symptomatic of some kind of hyperandrogenism. If the testosterone is over 200 ng/dl an ovarian ultrasound is used to look for any ovarian tumors. The higher the testosterone level the more risk of hirsutism or androgenetic alopecia if there is no corresponding rise in androgen antagonists (estrogens and SHBG).

Estrogens - Estrogens come in several shapes and sizes but the common one and the one usually tested for is estradiol (E2). Estradiol concentrations in women vary considerably depending on age and the stage of the reproductive cycle. The normal range may be anywhere between 50-700 picograms per milliliter. At the time of ovulation the range may be between 100-400 picograms per milliliter. Estrogens antagonize (cancel out) the actions of androgen hormones so more estrogen in effect reduces androgen hormone activity. As such, an estrogen level at the higher end of the normal range is preferable in terms of reducing susceptibility to androgenetic alopecia. Currently, there is much debate about how estrogens may directly act on hair follicles. Hair follicles do express estrogen receptors so the follicle are directly responsive to estrogen hormone molecules. However, there is confusion as to what estrogens do to the follicles - whether they stimulate or inhibit hair growth. There may be a different response depending on the estrogen type. Abnormally high estrogen levels on day 3 may indicate existence of a functional cyst or diminished ovarian reserve - however, there are no reports of hair loss in association with abnormally high estrogen levels so the risk of hair loss seems to be a minor one.

Dehydroepiandrosterone (DHEA) - Dehydroepiandrosterone sulfate (DHEAS) is the sulfated form of Dehydroepiandrosterone (DHEA). DHEA is a relatively unstable molecule and it mostly gets converted to DHEAS before circulating in the blood stream. For the purpose of understanding androgenetic alopecia, DHEA and DHEAS can be regarded as basically the same thing. If DHEAS is over 700 micrograms per deciliter, an MRI is ordered to rule out and adrenal tumor. If the DHEAS is between 500 - 700 micrograms per deciliter, then further endocrine testing is usually needed to rule out adrenal hyperfunction such as adrenal hyperplasia. An elevated DHEAS level may be improved through use of dexamethasone, prednisone, or insulin-sensitizing medications. DHEA can be converted into more potent androgen forms, ultimately it can be converted into dihydrotestosterone by enzymes in the hair follicles. As such, A high DHEA level potentially suggests an increased susceptibility to hirsutism or androgenetic alopecia if there is no corresponding rise in androgen antagonists.

Follicle Stimulating Hormone (FSH) - FSH is often used as a gauge of ovarian reserve. In general, under 6 is excellent, 6-9 is good, 9-10 fair, 10-13 diminished reserve, 13+ very hard to stimulate. In PCOS testing, the LH:FSH ratio may be used in the diagnosis. The ratio is usually close to 1:1, but if the LH is higher, it is one possible indication of PCOS. For healthy hair growth then, the ratio of FSH to LH should be roughly equal.

Luteinizing Hormone (LH) - A normal LH level is similar to FSH. An LH that is higher than FSH is one indication of PCOS.

Prolactin - Increased prolactin levels can interfere with ovulation. They may also indicate further testing (MRI) should be done to check for a pituitary tumor. Some women with PCOS and associated hair problems also have hyperprolactinemia.

Progesterone (P4) - An elevated level may indicate a reduced fertility. A progesterone test is done to confirm ovulation. When a follicle releases its egg, it becomes what is called a corpus luteum and produces progesterone. A level over 5 probably indicates some form of ovulation, but most doctors want to see a level over 10 on a natural cycle, and a level over 15 on a medicated cycle. There is no mid-luteal level that predicts pregnancy. Some say the progesterone test may be more accurate if done first thing in the morning after fasting.

Sex Hormone Binding Globulin (SHBG) - Increased androgen production often leads to lower SHBG. This is a potential problem in terms of hair growth as SHBG is an antagonist to testosterone. SHBG binds to testosterone and renders it inactive. Bound testosterone cannot interact with androgen receptors on cells so it has no impact on hair follicles. A reduced SHBG level suggests a possible increase in susceptibility to hirsutism or androgenetic alopecia. The more SHBG there is the better in terms of healthy hair growth.



--------------------------------------------------------------------------------
Ah, Thank God for Copy/Paste - ya think...


Thank you Becca!!!!!
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