[quote name='janet c' date='Mar 22 2009, 09:08 PM' post='274334']
[quote name='frozentundra' date='Mar 22 2009, 08:59 PM' post='274332']
Water, Glycerin, Isohexadecane, Niacinamide*, Isopropyl Isostearate, Aluminum Starch Octenylsuccinate, Nylon-12, Dimethicone, Tocopheryl Acetate**, Panthenol***, Sodium Hyaluronate, Palmitoyl Pentapeptide-4^, Carnosine^, Camellia Sinensis Leaf Extract^^, Aloe Barbadensis Leaf^^^, Soluble Collagen, Elastin, Allantoin, Stearyl Alcohol, Polyethylene, Cetyl Alcohol, Sodium Acrylates Copolymer, Behenyl Alcohol, Benzyl Alcohol, Caprylic/Capric Triglyceride, Polyacrylamide, Dimethiconol, Peg-100 Stearate, Stearic Acid, Disodium Edta, Cetearyl Glucoside, Cetearyl Alcohol, Citric Acid, C12-13 Pareth-3, Laureth-7, C13-14 Isoparaffin, Sodium Hydroxide, Ammonium Polyacrylate, Phenoxyethanol, Sorbic Acid, Butylparaben, Ethylparaben, Isobutylparaben, Methylparaben, Propylparaben, Sodium Benzoate, Mica, Tin Oxide, Titanium Dioxide, Fragrance.*Vitamin B3, **Vitamin E, ***Pro-Vitamin B5, ^Amino-Peptide, ^^Green Tea, ^^^Aloe VeraIf this is the accurate list of ingredients, there is something further here to consider. The third item on this list is a
petroleum distillate. Basic research reveals it is a refined isoparaffin (paraffin as in wax candles as in derived from petroleum.)
IsohexadecaneIsohexadecane is a mixture of highly branched C16 isoparaffins with a small proportion of C12 and C20 paraffins of similar structure.
The main use of Isohexadecane is in high quality cosmetic and personal care products, where very low toxicity and skin irritation, and a lack of colour and odour are essential properties. Isohexadecane forms particularly robust emulsions (creams), which is an important feature for the product formulator. To the consumer, the non-greasy silky feel that Isohexadecane products leave on the skin is particularly appreciated. Foundation creams, sun care creams, lip creams, deodorants and antiperspirant sticks, make up removers and hair conditioners are amongst the products that have been formulated with Isohexadecane. The known poison data for isoparaffin is located here:
http://www.pesticideinfo.org/Detail_Chemic...C33012#ToxicityThis substance may potentially be an endocrine disruptor, as are MOST petroleum based products or dstillates.
As for the parabens, here is research and factual data provided by a womens breast cancer reearch group:
http://www.breastcancerfund.org/site/pp.as...E&b=1203361Without going into greater detail, it appears that this particular product contains not only a significant grouping of parabens but other synthetics and near the top of its list is a petroleum distillate, which may be highly concentrated owing to its purification data, and it is a potential endocrine disruptor. If you put this date together, without even researching the other synthetic elements in this product I think you will find your answers as to WHY it may be affecting you and that it, in fact, may indeed be accumulating in your tissues. Not as I suspected originally based on the niacinimidec content but perhaps in your estrogen receptors as was originally speculated. I think Olay needs to conduct a study utilizing 1500 40-70 year old women and run some baseline endocrines on them as well as standard baseline functions with CA marker tests and then place this group on a controlled daily useage of this product for 6 months and retest ALL at the conclusion of the trial.
The niacinimade is particularly hard to absorb through the skin without providing it a special transdermal vehicle. If the vitamin were heated to liquefy it would likely damage its effectiveness. Therefore, it seems reasonable to assume it may require the highly concentrate, purified isoparaffin to create that delivery system. What delivers the vitamins in this product will also deliver the parabens/potential endocrine disruptors equally effectively. If it is being stored in fatty tissues as an oil based product, it could certainly accumulate quickly and hold an effect over a period of time. I would like to see precisely what form of niacinamide is used and whether there is any evidence that it can be made bioavailable transdermally at all.
There are two critical factors to be examined within this product profile. The first is the vitamin profile which may or may not be equally effective or effective whatsoever at the skin level of women, based upon its purity and transdermal delivery factors and the second is accumulation data for the paraben/petroleum distillate profile...which is far more extensive than I had initially suspected. To summate; without better data it is impossible to indicate or indict these factors for exerting the influences described. Studying the ingredient data supplied, I do not believe the symptoms being described are psychosomatic.
For those ladies who reported a regular useage without the positive results reported, were you at that time on ANY hormone replacement including but not limited to creams, soy useage or isoflavone useage?
For those ladies who report excellent results beyond skin softening properties, are you using any form of hormone replacement including any natural forms as listed above?THANK YOU!
[/quote
Oh goodness me-sooo technical! Would you like to contact Olay and advise them what tests they ought to be running?
Good luck with that!
janet c