Vitamin D is sometimes viewed as a non-issue for CFIDS except when following a protocol like that at marshallprotocol.com. It is my opinion that Vitamin D is an important adjunct for recovery from CFIDS (regardless of protocol). Boron may be an assistant to Vitamin D.
I believe that Dr. Mercola, MD recommended optimal levels for Vitamin D is correct.
45-50 ng/ml or 115-128 nmol/l [source]
This is some information that I had on file about Vitamin D levels...
The following table indicates how much supplementation is needed (over a 6 month period) to reach these levels.
Daily IUs of D 50 ng/ml 128 nmol/l
11281 5 13
10028 10 26
8774 15 38
7521 20 51
6267 25 64
5014 30 77
3760 35 90
2507 40 102
1253 45 115
0 50 128
Based on 14 nmol/l = 1371 IU
Vitamin D Miracles
Sunlight and vitamin D are critical to all life forms. Standard textbooks state that the principal function of vitamin D is to promote calcium absorption in the gut and calcium transfer across cell membranes, thus contributing to strong bones and a calm, contented nervous system. It is also well recognized that vitamin D aids in the absorption of magnesium, iron and zinc, as well as calcium.
Actually, vitamin D does not in itself promote healthy bone. Vitamin D controls the levels of calcium in the blood. If there is not enough calcium in the diet, then it will be drawn from the bone. High levels of vitamin D (from the diet or from sunlight) will actually demineralize bone if sufficient calcium is not present.
Vitamin D will also enhance the uptake of toxic metals like lead, cadmium, aluminum and strontium if calcium, magnesium and phosphorus are not present in adequate amounts.18 Vitamin D supplementation should never be suggested unless calcium intake is sufficient or supplemented at the same time.
Receptors for vitamin D are found in most of the cells in the body and research during the 1980s suggested that vitamin D contributed to a healthy immune system, promoted muscle strength, regulated the maturation process and contributed to hormone production.
During the last ten years, researchers have made a number of exciting discoveries about vitamin D. They have ascertained, for example, that vitamin D is an antioxidant that is a more effective antioxidant than vitamin E in reducing lipid peroxidation and increasing enzymes that protect against oxidation.19;20
Vitamin D deficiency decreases biosynthesis and release of insulin.21 Glucose intolerance has been inversely associated with the concentration of vitamin D in the blood. Thus, vitamin D may protect against both Type I and Type II diabetes.22
The risk of senile cataract is reduced in persons with optimal levels of D and carotenoids.23
PCOS (Polycystic Ovarian Syndrome) has been corrected by supplementation of D and calcium.24
Vitamin D plays a role in regulation of both the "infectious" immune system and the "inflammatory" immune system.25
Low vitamin D is associated with several autoimmune diseases including multiple sclerosis, Sjogren's Syndrome, rheumatoid arthritis, thyroiditis and Crohn's disease.26;27
Osteoporosis is strongly associated with low vitamin D. Postmenopausal women with osteoporosis respond favorably (and rapidly) to higher levels of D plus calcium and magnesium.28
D deficiency has been mistaken for fibromyalgia, chronic fatigue or peripheral neuropathy.1;28-30
Infertility is associated with low vitamin D.31 Vitamin D supports production of estrogen in men and women.32 PMS has been completely reversed by addition of calcium, magnesium and vitamin D.33 Menstrual migraine is associated with low levels of vitamin D and calcium.81
Breast, prostate, skin and colon cancer have a strong association with low levels of D and lack of sunlight.34-38
Activated vitamin D in the adrenal gland regulates tyrosine hydroxylase, the rate limiting enzyme necessary for the production of dopamine, epinephrine and norepinephrine. Low D may contribute to chronic fatigue and depression.39
Seasonal Affective Disorder has been treated successfully with vitamin D. In a recent study covering 30 days of treatment comparing vitamin D supplementation with two-hour daily use of light boxes, depression completely resolved in the D group but not in the light box group.40
High stress may increase the need for vitamin D or UV-B sunlight and calcium.41
People with Parkinsons and Alzheimers have been found to have lower levels of vitamin D.42;43
Low levels of D, and perhaps calcium, in a pregnant mother and later in the child may be the contributing cause of "crooked teeth" and myopia. When these conditions are found in succeeding generations it means the genetics require higher levels of one or both nutrients to optimize health.44-47
Behavior and learning disorders respond well to D and/or calcium combined with an adequate diet and trace minerals.48;49
Best Wishes,
TJ