I put myself back on a regimen of topical progesterone cream about 10 days ago (on the 14th day of cycle) and noticed a few changes in mood and anxiety levels. Both were affected in a negative way. But the most interesting side effect was with the condition of my gums. Within a week of being on this hormone, they became red, puffy and tender. Terrible breath ! It felt like my teeth were coming loose on the top ! All the classic signs of gingivitis - so I researched it on the web, and sure enough there is a correlation between excessive levels of progesterone and healthy gums. Lots of pregnant women have problems with gingivitis because of the high levels of progesterone.

Wow. It's like everything I do to try and alleviate some of these worrisome symptoms just backfires on me ! Has anyone else experienced this ??

I had senstivie gums from using oral prometrium. And, I developed horribly painful cold/canker sores in my mouth too.

Yes, everything I do also backfires on me! I tried bio progesterone cream, and HRT and BCP and herbals and acupuncture (hard to believe that this backfired but it DID)...sleeping aids, too many vitamins...I am throwing up my hands and throwing in the towel and up goes the white flag...I give up....YOU (menopause) WIN! Joan

Hi slowbear,

I react strangely to lots of stuff too. I'm on my third acupuncture treatment and I'm unsure about it. How did acupuncture backfire for you?