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gaylyn
Has anyone had any problems with hormone replacement therapy?   Anyone experience cancer from the hormones?   Most everyone that I have spoke with (who have been on hormones for over 8 years) have had no problems whatsoever.
Patricia
QUOTE
Quote: from gaylyn on 6:42 pm on May 16, 2001[br]Has anyone had any problems with hormone replacement therapy?   Anyone experience cancer from the hormones?   Most everyone that I have spoke with (who have been on hormones for over 8 years) have had no problems whatsoever.
Hi GaylnI do not take HRT myself...but a close friend of mine has been taking this now for over 10 years + she developed thryoid cancer about 6 months ago....but all is ok now....and she is still on the meds -smile.gif
toxicterri
I  took premarin for 7 years after surgical menopause.  I didn't have any problems, except severe loss of libido.  I quit last year after I got breast cancer.  I am sure it was the premarin that caused the cancer.  So, I was thrown into my 2nd menopause.  Started tamoxifen 4 months ago - menopause #3 - and I'm only 41!  Going off the premarin did seem to bring my sex life back to life.
victoriasecret51
I was on HRT for a while myself and had to stop HRT because I developed breast cancer, went into menopause because of the chemo.There is an article here that I find very interesting!www.usatoday.com/news/acovwed.htm
brownowl
I have had a lot of problems with oestragen implants.three years ago I was having double and trebel vision I went off my legs dizzyness and lethergy I could not get out of bed. It was found that I had been overdosed with oestrogen. The last three years I have not left my home only for doctors appointments as I have been so ill.I suffer daily from giddyness feel sick feelings of  faintness and a feeling in my head that I can not describe I am so off balance . HRT has been hell please be carefull . I am now trying alternatives but no luck so far. Has anyone else been overdosed and is there a light at the end of this very long tunnell.only found this site today hope I am doing it ok this is the first chat room I have been on.many thanks brownowl
Ga Girl
Dear Brownowl:I  have been on Premarin for 3 years and have just started having problems about 2 months ago.  I did not even think it could be the hormones.  I quit taking them a week ago.  So far, I still have dizziness, vision problems, buzzing sensations in my whole body, including my head and mouth.  I believe it is an overdose of Premarin, but only time will tell.  I read it takes 8 to 11 weeks after last dose to get better.  It doesn't sound like that is working for you.  Were you on Premarin?  I feel like I swapped the devil for the witch with this hormone therapy.  Hope you are better soon.  My prayers with you.Ga Girl
brownowl
Hi Ga Girl sorry to hear you are having trouble with HRTI am not on premarin I live in the UK and we still use pellet implants and this is what I have been on since my hysterectomy in 1994. I have tried a lot of pill and patches gell the lot  and  with no success. Thats why they gave me a hysterectromy plus removal of  my overies  they said all my troubles would be over how wrong they are.I was implanted with oestrogen every 5 months but my doctors never took blood tests so the oestrogen just kept on building up in my body. Doctors do not listen they think they are always right. When I refused anymore implants and the doctor took a blood test it was found I had a level of 1560 it should not have been any higher than 400. I have now been told there is nothing they can do untill my level comes down to below 70 this could take years they just dont know. I have been off all HRT for 3years and 5 months and I am still suffering every day.There are many women in the UK who have been affected by HRTTry and get a blood test done , I dont think it takes as long to leave your body if you are on pills lets hope not.We just dont know what this HRT is doing to us. we need more information as we can make our own minds up. I have learnt alot over the past year and if I knew then what I know now I would never have taken HRT. I hope I can reach out to women and share my experiances I would not want anyone to go through what  I am going through It is HELL.Have you looked up premarin and the problems it has caused?My thoughts are with you lots of hugsbrownowl.
Ga Girl
Dear Brownowl:I have been reading on the side effects of Premarin and I do have some of them.Not sure if it is the Premarin itself or the dyes on the pills.  My doctor wants me to have MRI to determine if anything else is going on since I had back surgery 15 months ago.  I am off everything now and hope I will get better soon.  I think because of all of this, I have worked myself up into a "fit of anxiety"' as well.  I feel the same way--if I know then what I know now!  Hugs  to you too.  Hey--anybody else out there had side effects to HRT?Ga Girl
Snowbird
Hi'YaWell Ga Girl.....YOU asked a question I just COULDN'T resist!! :biggrin:I've had more problems....side effects with HRT than I care to list....but I'll give it a shot....errr.....the short version!! Cause....I could write a book....before the movie!! :cheesy:

Been on HRT for 9 years....Premarin and Provera...mainly!!  Here in Canada it's what they use most!  I took it to stop Hot Flashes....which it did!!  However, within a couple of years I started breakthrough bleeding....persistant yeast infections....constant dizziness...thyroid problems....gallbladder disease!!  Had the gallbladder removed!! Yikes!!  Part of my thyroid removed, as well....now taking meds for that!!

The docs tried different forms, dosages etc. of HRT with me....nothing worked!!  As time went by....especially the dizziness....and oh yeah....thos dang buzzing sensation!! *Sheesh* I hated that! mad.gifI'd got so dizzy....I was like a drunk....incoherant....had the shakes....was halucinating!!Althought....I never had a hysterectomy....I was still having bigtime problems with HRT! I had to stop taking it......it took 3 months to leave my system!!  I was withdrawing all during that time!

Later I found out.....two things!! *PREMARIN WAS POISON to me* ohmy.gif It comes from horses....and I'm NOT a HORSE!! :biggrin:  My body was reacting accordingly!!!!!!!  The PROVERA was being rejected also.....because I was "estrogen dominant" and the balance was up and down, DUE to hormonal fluctuations during peri!!  Although we're talking mainly Premarin here.....I personally don't like it.....because for one, it's not Bio-Identical.

Bio-Identical hormones by definition means that the hormone is chemically identical to the hormones that are produced by the ovaries.  Tri-Est and Bi-est are two examples. Tri-est is made of all three estrogens, that the ovaries produce (estriol, estrone, estradiol)....Bi-est is made of estriol and estradiol only.

A MRI couldn't hurt.....it's always a good idea to rule out any other problems.....like myself.....after an ultra-sound, gallbladder disease was found!!

I'm not a fan of Premarin.....Provera fought what my body was trying to do.....the two together fought each other... caused the uterine lining to build-up that could have become cancerous....but didn't!! *Thank God*The scare put me off all HRT....now I'm going through meno again...but it's getting better!!

There are other alternatives, than Premarin!! Some gals have found the Bio-Identical compunded estrogens help....the Natural plant compound, (although it didn't help me).....soy, hebs, etc.  It's really a matter of education....sometimes trial and error....and seeing what others have tried, (like you're doing)!!  Everyone and I mean everyone is different!! What works for one, may not for another!!

Hope that helped a little....I know it can be frustrating at best....but, we all make it!! :cool:

Take care and God Bless..........

((((((((((Hugs from a Canadian Chick))))))))                        Nancy

Ga Girl
Hi Nancy:Thank you for your reply.  Hopefully, all of these side effects will disappear soon. Did you have any muscle twitching or cramping in your legs because of this?  I am hoping this is related to that and not anything else! I guess if we had taken Premarin any longer we might have grown a tail!  I will never take it again.  God Bless You and we will get through midlife with His help.Ga Girl
Dearest
Gaylyn, it may be that most people you have spoken with have had no problems with HRT, but it's been my experience over 7 1/2 years of running Power Surge that the majority of women who use HRT have problems with it, which accounts for why so many women stop taking it within the first year of starting.

I believe the #1 reason for women not using HRT are the risks involved with using it and secondly, the side effects most will have. To those who have mentioned Premarin, I realize it's the oldest estrogen replacement therapy on the market, but so many new modalities have been discovered for delivering hormones that Premarin is outdated.

There are those doctors who, for various reasons, insist on prescribing Premarin. If I went into all the perks they get from the pharmaceutical companies for prescribing certain drugs, it would take an hour to post. Bottom line is that Premarin, Prempro and Premphase are made from the urine of pregnant mares, hence the name PRE-MAR-IN. If that weren't enough, the way the horses are treated during the time their urine is extracted is cruel and inhumane. Power Surge has stated its objections to the animal abuse involved in the manufacture of these drugs. You will find articles about it on the Web site. You can do a  search to read more about Premarin.

The mares spend at least six of the 11 months of their pregnancy tied in stalls in which they can tread in place but cannot turn around. They are exercised outside their stalls no more than once a week; some are not let out from mid-September until late March. In many cases,  the stalls are too small for horses to lie on their side, their natural sleep position, or to groom themselves, and the horses are kept thirsty to keep their urine as concentrated as possible.

Every time I think about it, I feel ill. There are numerous options to Premarin. I would recommend looking into bio-identical, naturally compounded hormone therapy for those who want to take hormones which, by the way, is not a goes without saying thing for women in menopause. Contrary to what many doctors would have you believe, every woman doesn't develop heart disease, osteoporosis and shrivel up to a dry, old woman when she becomes post-menopausal just because she's NOT using hormone therapy.

Those interested in finding out more about naturally compounded hormones should read the transcripts of pharmacist, Pete Hueseman, in the Library. Also, check out the recommendations page for many of the options available to you.

Dearest

Framboise
The saddest thing about hrt, as Dearest notes, is the high level of women who abandon hrt after a bad experience with side effects. So many times, these are really the effects of imbalanced hormones, and hence the side effects of badly-managed hrt, not the hrt itself. The medical literature is gradually coming to recognize this, with several major articles in the past couple years noting that (oh gee, what a surprise!) women do better on individualized hrt. Still, the pharmaceutical company-driven system of perks and rewards to doctors is a powerful force working to combat this trend in favor of the one-size-fits-all school of take-your-premarin-or-nothing. This basically forces women to be their own research projects. At best, we stumble onto a particularly enlightened doctor or enlist the services of our new allies, the compounding pharmacists. At worst, we chuck the whole thing as a bad idea and crash headlong into the further briars of non-hormonal menopausal support, still on our own and at the mercy of all of the unregulated sales pitches of the world with little science to guide us. The internet and the capability it has provided women to get together and learn they are not each alone in this journey is one of the most empowering things that has happened to menopause since the discovery of hormones.

I think it's also important to acknowledge the differences in hrt use and tolerance between women in natural meno and women without ovaries. For the former, the whole process is vastly complicated by the natural swings of ovarian output, making any regular supplementation guaranteed to be imbalanced a certain percentage of the time. The risks to the endometrium further dictate hrt limits, with a need to be concerned about feeding endometrial overgrowth. For the latter, I feel there is a much stronger indication for persisting in looking for balance, since we lack that reservoir of limited hormone output that post-menopausal ovaries provide those who still have them, and unless we have most unusual metabolisms and a high intake of xenoestrogens, we can rarely meet our needs with non-hormonal measures. (Please note these qualifications--I know there are those out there who fall into the category of exceptions, but close observation of this body of women indicates that they are indeed exceptions to the norm.)

I also continue to be saddened by the heavy press given to risks of smaller statistical incidence (but high emotional freight) than the benefits of hrt. Obviously, there is a need for personalization, and nowhere is this more important than in assessing the risk/benefit ratio for a specific individual. But the fact is that "this causes cancer" is a phrase that destroys our cognitive ability to look further into the fact that there are many things that affect or can be done to prevent that cancer, and there is some justification of the premise that some of the stats (I'm talking about breast cancer here) reflect better detection due to the increased medical care contact of women on hrt as opposed to those not getting regular medical supervision.  The risks are real, but the fact that they overshadow the benefits and short out the process of individual evaluation robs, I believe, women of the option of giving practical consideration of something that could be of real benefit to them.

I'm not arguing with you here, Dearest--I'm agreeing and decrying the fact that our perceptions and choices and the process of trying to find and use an hrt without all these burdens are driven by commercial concerns (sales for the pharmaceutical, insurance, and media companies) rather than our well-being and health. In a world ordered by menopausal women (well-balanced menopausal women, I hasten to add!), premarin would exist as an historical footnote, women would shop a palette of natural/bioidentical choices with knowledgeable guidance, and synthetics would be reserved for those whose bodies are too frivolous in their interconversion of the hormones. Sigh.

Until then, I'm so glad we have each other.

Snowbird
QUOTE
Quote: from Ga Girl on 7:20 am on July 14, 2001[br]Hi Nancy:Thank you for your reply.  Hopefully, all of these side effects will disappear soon. Did you have any muscle twitching or cramping in your legs because of this?  I am hoping this is related to that and not anything else! I guess if we had taken Premarin any longer we might have grown a tail!  I will never take it again.  God Bless You and we will get through midlife with His help.Ga Girl

Hi, again!!

Yup....one of the most annoying and freightening sid-effects I had was the muscle twitching in my legs!!  Day and or night!!  Even tho I have fibromyalgia.....the twitching was different and more intense!!  It would wake me up out of a deep sleep....and would even be painfull!! :oNow...any muscles twitching I have (or spasms) is fibro related and not....NOT scary!!  At least I can deal with that........as before it just didn't know what the heck was going on!! :angy:Yes.....it definitly is getting better....Thanks;)  Like I said, some gals go through a real tough time with HRT!! I appreciate your concern!smile.gif

((((((((((Luv ya and HAGO))))))))))                  Nancy

Ga Girl
Thanks Nancy.  It makes me feel better about the twitching because they are sending me for an MRI on July 24.  I have been to 3 doctors and they don't seem to have a clue. Not one of them mentioned Premarin until I deided that could be the reason.  Now I feel like I am on an emotional roller coaster since I have been off the stuff.( 0nly one week) . I guess that will take a few more weeks to get straightened out--if my family doesn't kill me before then.  Everything seems magnified and I feel like crying a lot of the time--what a mess!Thanks again for your reply and God Bless.Hugs to you , GA Girl
Snowbird
((((Hang in there Hon))))))

These things take time!! *Sigh*  Wish I could snap my fingers, and make it all go away!!  It may take another week or so....and you should feel some improvement.......not totally gone....but you'll notice something, IF it's the Premarin doing all the fuss!!  IMHO....it sure sounds it!! If they find anything else, the MRI should show something!!

The emotions take a real beating at this time.....poor hubby....didn't know whether to run, hid...or just keep quiet!!  Think he did all the above.....:biggrin:

Keep me posted!!

((((((((((Luv ya)))))))))))           Nancy

Ga Girl
Hi Nancy:Just one more question about your ordeal with Premarin.  I don't know how to describe this sensation, but sometimes I feel like I have a buzzing sensation in my face and head.  I think it has gotten better over the last week, but not gone yet. The twitching or muscle spasms seem to be in mostly my right leg and foot.  I think I get so worried that makes it even worse.  It's barely noticeable during the day, but aggravating at night.  I can already tell that my bladder problems are better--I don't have to get up every 2 hours at night--only every 4 which is normal for me. I'm still having the paplitations which I understand may stay with me from what I have read about meno. I'm glad to have someone else who understands this.  I thought I was just going crazy. Thanks meno bud!Love ya, Ga Girl
Snowbird
Ga Girl...Morning...Meno-bud!!

That buzzing you're talking about.....I had it!! mad.gif  Most annoying and frightening ohmy.gif  It interefered with my cognitive abilities too....like THINKING!!  I'ts sort-of like the beginnings of a ~~Hot Flash~~without the heat, (on the face)!! I think it's because the body was rejecting the hormones I was forcing it to take!!  I still get the buzzing....it comes with the occational Hot Flash....but it only lasts a split second or so and not scary......now that I know what it is!!Hormones are such a tricky thing!!  They control so many areas of the body!!Take care my friend and if you have any other questions.....just fire away....if I can answer, I will!!

((((((((((((Hugs from Snowy))))))))))))                      Nancy

Ga Girl
Thanks for all your help.  I just can't believe I feel like this--up and down, up and down.  Hopefully, some of this will be gone in another week.  Once I go to the neurologist I hope I will feel better about this.   I had back surgery 16 months ago, so some of this foot  and leg twinges and muscles could be from that, but it sure took a long time.  I still think it must be the HRT as all of these symptoms all kind of came at the same time.  It even affected my vision some.  What , if anything, are you on now?  I still have my ovaries (for what good it does), so I wil have to determine if I want to go on some other kind of HRT.  Thanks for everything. Take care.Ga Girl
Snowbird
Hi, Ga Girl!!Hope you're feeling better today!!;)After my experience with HRT....I decided to not try anything else where hormones are concerned!!  Altho' I did try soy and some herbs, but .....alas....hives,  I was allergic!!  So....at that point I just gave up the whole idea, and decided to go natural! Dunno, if you can do the same, as you've had a hyster......but like you said....you do have your ovaries.....so maybe it will be OK!!  I have a girlfriend, in the same situation as you, and she isn't taking anything. Claims, to be OK!! Althought she does have a few mood swings, and irritability, along with some insomnia!!

Anyhoo take care my friend and HAGO :biggrin:

((((((((((((Hugs from Snowy))))))))))))                      Nancy

Sue
Well I must add my 2 cents or pennies(I was born in England)came to Canada when I was 19.nyhow I took Premarin for almost a year and it was a year of hell,high blood pressure stomach problems gall bladder attacks my migraine that were bad enough became unbelieveable,concentration level 0(as if it wasn't bad enough already)tell me when to stop.My mistake was when I was home (UK)on holiday I quit cold turkey and ever since then my hair has been falling out and is not growing back very stressfull.I did go back on ERT to help my hair so my doctor said,but this time a patch Estraderm it works very well for me gradual dose all day not going directly through my liver.most of my side effects have gone,except aches and pains arms leg etc.Hope all works out for you girls.I had hysterectomy  99 kept the ovaries but the conked out a year later typical!!!!!!My mum was just here for a visit and she brought me Starflower gel tablets to help with the hair,I am trying them the bottle says for Hormonal Harmony!!!I would now like to stopp ERT but am afraid about all my hair falling out I did have really nice hair now UGH!!!!with all the other rubbish going on with menopause I don't need this.Soon I won't be able to go outside.Started meno symptoms when I was 36 I am noe 43,most off the women on my mum's side have gone through early menopause.Sorry this turned out to be soooo loooong.
Ga Girl
Hi Sue:Sounds like Premarine got a hold of you too.  I wish I had never heard of that stuff.  Hope all goes well with your health now.  I know your hair situation will get better.  These things just take time.  Hormone Harmony, huh, do you think there is any such thing?  I hope so for all of us.  Good luck with everything. HugsGa Girl
Ga Girl
Hi SUE:when you were on Premarine or coming off of it, did it cause you to have any muscle spasms or twitches?  I have been off for almost 3 weeks and this seems to be one of my biggest problems.  Just didn't know if it was related.  Also, have had major headaches.  Hope you have a good day today. Hugs, Ga Girl
Dearest
This was sent to me by new member, Brownie, via messenger. I'm posting it here for your feedback. Message title: Problems with HRT

I am 56 years old and have been on some sort of hormones since the age of 44.  From age 44-50, I took a low-dose birth control pill, from age 50-54, I took Premarin (with bad side effects), at age 55, I switched myself to the Vivelle Patch (.375) and Provera (2.5) and I started to feel much better.  Now at age 56, I started to suffer from depression and spotting, so I found another doctor (female) who switched me to Ortho-Prefest.  When I started on this new med, I had severe side effects (bad headaches, palps, dizziness, nausea, hyperness).  I started to take 1/2 the dose (cutting the pill in half).  I called the doctor and she told me that maybe it was time to wean myself off of HRT.  I started to do that by taking 1/2 pill one day and then nothing the next day.  I feel 100% better - have more energy, the depression is completely gone.  While still on the Vivelle Patch/Prometrium, I started with severe vaginal dryness for which my new doctor prescribed Premarin Vaginal Cream and that has helped tremendously.  I still have my uterus and my mother had breast cancer.  Do you have any advise for me? Thank you for this wonderful Message Board - It is a "God Send"!

Gratefully yours, Brownie

Sue
Hi Ga Girl.Thanks for your response I pray the hair situation settle's down as well.I seem to remember aches and pains and leg muscle spasms,to be quite honest I was feeling so bad,nothing seemed right with me.Do you have migraines??as I saidbefor mine were constant and bad very painful I felt sick with them.In hind sight I would never have taken any ERT and I do blame myself because when the GYN prescribed them I should of asked question and I didn't.I was hardly ever sick or felt ill until ERT.I no it works wonder's for some women and I am glad for them,on the other hand the patch is better for me as well its a low dose 0.50.Well have a great weekend,its my 25th wedding anniversary so we are going away for the weekend,e-mail anytime.
Ga Girl
Hi SUE:Well, I started on the Climara patch yesterday--so far I still feel like running away!  I know it will take a few days to see if it makes a difference.  I hope  it clears up some of this trembling and shaking.  I feel like my head is going to spin off at night when I go to bed --and most of the day too!  This is an awful feeling. Congratulations on your anniversary--have a great weekend.  I had my 30th one in May.  We are very fortunate as many marriages don't last this long.   I think if you can live through menopause you can handle anything!  HUGS from the SOUTH.

Ga Girl

dixiemartin
Ladies: I can't take hormone replacement because I've had fibrous of the breast and thank god not cancer. My doctor told me never to take the hormon because it feeds on it and could turn into something worse.  I choose not to take it.My question is: What should I do so I don't get the hot flash and can sleep.  I don't do well on any medicine.  That 's another story.Right now I've had for three days itching inside like hemorrides so I used so cream. It helped but then  it iches around the area too.  I don't know how else to say that so Sorry. Please if someone could give me advise, that would help.  I'm healthy. Thanks Dixiemartin
Snowbird
Dixie, Hi!You are a wise woman for deciding not to take HRT, because of the fibrous situation of you breast!I avoid HRT for other reasons.....but have you considered soy products and or herbs??  Some gals have good results with these products for Hot Flashes!I can't take them due to side affects and allergies....but not everyone is like me:biggrin:I still get~~~~Hot Flashes~~~~~~:(Had one yesterday:oSince I really don't take anything for them.....what I do, is take an ice pack to bed and keep it near me, (if I need to find it in a hurry).  I have air-conditioning....plus a fan nearby....which I adjust to suite my situation!!Hubby, so far doesn't mind....cuz....he likes it cool, thank God.....or someone would be sleeping in a different room;)

Don't know if that helped or not....as my options are quite limited!!  Maybe someone else can add to what I just posted for you.Hope you're feeling better soon! I know these things can be a drag at times:(

(((((((((((((((Hugs from a Canadian Gal)))))))))))))))                                Nancy

jeanne
Hi dixie,You have to watch what you eat also. Caffeine , too much  sugar, too much carbs can make hot flashes worse. But especially caffeine. Since I changed my diet to no caffeine , if i do get a hot flash it doesn't last long and is tolerable. not as much sweating or trouble sleeping. Hope this helps, hugs , jeanne
Sue
Well I have decided to stop ERT(patch)I am cutting back from .050mg to .025mg,then i will stop altogether.Please everyone pray that the hair I have left does not fall out.I am going to try a naural replacement .I have read alot off pro's and con's about ERT and want to do whats left off menopause naturally.Its been 7 years already and I am only 43.The breast cancer risk is worrying as well as I have firbroids.After reading some info on ERT/HRT I do not know why my doc prescribed then Its been 22 yers off hell.Ga Girl I had a great weekend
Dearest
Hormone Replacement Therapy isn't for everyone. You may want to try soy isoflavones/protein -- try reading the Revival board. I've been using it for three years. Due to so many E.mails from women asking me about it, I decided to put a page up on the site about my experiences with Revival. I was using soy years before discovering Revival for all the good things it did for my body, but nothing stopped the hot flashes, night sweats, fatigue and depression the way it has.
Sue
Dearest.Thanks so much for your reply,a very interesting article I am hoping to find Revival in the stores here in Canada,I might be better off looking in a health store first.I did try soy milk befor but didn't like the taste or feel of the drink,thanks again and wish me luck on this road to who knows where????this menopause stuff is for the birds.I get soooo confused at times about ERTI have to admit that I have been on it twice the second time out of deperation to get my hair to stop falling out and grow,but alas after 9 months no sign off any hair just more scalp.I find it very depressing at times hard to get out of bed in the morning,I am sorry you don't want to listen to that do you.I only hope that my hot flashes do not return and the anxiety etc,etc.But I do feel good about my decision to stop ERT.I know some ladies do well on it and I wish them all the best.Thanks,take care,the temp here today is 34c humidex 44c I'm dying ugh,for this part of Canada its HOT.
MaryO
Sue, Revival isn't sold in stores.  They're avoiding paying the middleman and keeping it fresher by not having it sit on store shelves.   You have to call them or order online.  There's more info about that on the Recommendations Page.

I hope it helps you as much as it has me for these last 3 years!

Sue
Thanks Mary O,I am off to get their phone #.You ladies are great.Sue
Karen2413
Hi I'm pretty new here but wanted to respond about the muscle spasms and twitches from taking estrogen. I had this only when I used premarin and cenestin as they both have some of the same chemicals (cenestin/no mares urine). I think its from some side effect from some chemical in it .  I read somewhere that premarin stays in your body for weeks depending on long you took it. I now am on the patch and no longer have this. Also when I was on the premarin andcenestin I was taking rather large doses  so maybe this is why too. Side effect from too much estrogen.This is just a thought and no way meant to trash premarin or cenestin as for some I'm sure its been great. Have a nice day.
boni
I Have been on HRT for 10 yrs,had a difficult time in the beginning. Needed a high dosage of estrogen and 10mg of Cyrin (provera) 12 days a month.  Now as I am nearing meno my hormones are so out of whack that I cannot get in balance.  For the last 5 months it has been a nighmare. sad.gif   My body is rejecting everything,  Now I am on a Estrogen injection  along with a combo pill.   It has not been easy.

The journey is long, the detours are many, but along the way are new friends to guide you thru...smile.gif

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