I wonder is anyone out might have the answer to this question? Early meno, age 42, and the roller coaster of HRT is no fun at all. Estrogen no problem, but progesterones, one and all, are horrible. I asked M.D. last  year about vaginal Crinone, but he said it wasn't approved in USA for HRT. Now I find it on the Columbia Lab website. Does anyone know if this has now been approved for use is America? (Crinone gel 4% or Crinone gel 8%) I would really, really appreciate any information! Thank you so much!