I started taking Estrogel (estradiol) and Prometrium a few days ago. Everything seems to be going fine except that my anxiety levels seem to be higher and I feel depressed. I'm wondering if anyone could tell me if maybe it's because I switched from synthetics and this will take sometime to get adjusted, or is it because I'm not absorbing the Estrogen ( gel form ) or the Progesterone is not enough. I was really hoping that this new bioidentical regimen would work for me. I feel so discouraged and at the end of my rope. What could be causing this anxiety , too much or not enough ? Man this is a drag !!!!