***I have been on prempro for about 7 months. I have had no menopausal symptoms or bleeding while on it. Sounds great--but I also suffer from vulvodynia ( constant discomfort in the vulva area for no apparent reason. Please google for more info ). Since the prempro my pain in the area has gotten worse. I thought if I switch to estrace oral and prometrium it might help me because these products are more natural. I also don't feel prempro is good for you--but was given no choice at the time. I have since changed gyna's and am hoping she will help me make the change. Has anyone done this? I thought I would take estrace twice a day ( a total of 1mg ) and the prometrium at 100mg. Does this sound right? I was wondering how anyone out there feels on estrace/prometrium. I would be thankful to hear from you!
Debe2

Yes Debe2 this dosage sounds rights to start off with. I take my estrace twice a day and prometrium right before bed. I started taking the bhrt to stop heavy bleeding around 15 months ago. I take 2 mg. E and 100 P on days 5-14 then up the P to 200mg days 15-25. You may need to adjust your hormone levels after a couple months. I recommend you keep a log of daily symptoms. I use a scale of 1-10 to determine how well I feel each day and chart any problems/discomfort. When I began noticing a pattern of breakthrough bleeding at mid-cycle and headaches when I cycled off them to get a monthly period I had to make some adjustments. It's not always perfect but I'm certainly in ALOT better shape than I was a year ago. I love the Bios,the estrace gives me energy and the Prometrium helps me sleep.
Good luck to you.

***Thanks for the info! I plan to take mine continually-I don't want a bleed. I'm glad it is working for you. Hopefully it will work out for me!
Debe2