I have been on Premarin & Provera mix for 5 years and it has worked great!
When I went to refill my prescriptions, they only had the provera because the Premarin got too expesnive to carry so it was discontinued. They suggested ESTRACE as a compariable alternative. I did some research, and according to all the documents 1.0 ESTRACE is compariable to the 0.625 Premarin I am taking. However the doctor only prescribed Estrace 0.5 dosage. Does anyone know what kind of a difference this would make. Currently I am taking 0.625 Preparin & 1.25 Provera, which was the actual combination of PHREMPHASE that I origially took, but when it got to 47$ a month, this system I am using now is much cheaper. I am just curious if anyone esle went from PREMARIN to ESTRACE, and how it worked for them. So now that I have rambled..my actual question is: .05 Estrace compariable to 0.625 Preparin? thanks

Hello....

I did a little research and found the following information from earlymenopause.com.....

HRT Equivalencies

One of the most common questions where hormones are concerned is what dose of one form is equivalent to another. For example, if you've been on .625 Premarin and want to switch to an estrogen patch, what would give you roughly the same amount of estrogen?

Here's a quick rundown to make matters easier. Keep in mind, though, that not only are these rough equivalencies, but also that your body may react differently to the individual forms of HRT. In other words, the same dosage in different types of HRT might have more or less of an effect on your body.

ESTROGEN

Type Daily Dosage
Conjugated estrogen (Premarin, Cenestin) 0.625 mg
Estradiol (Estrace) 1.0 mg
Transdermal estradiol (patches) .05 mg (50 mcg)
Estropipate (Ogen, Ortho-Est) 1.25 mg
Esterified estrogen (Menest, Estratab) 0.625
Tri-est/Bi-est 2.5 mg
Ethinyl estradiol .01 to .015 mg (10 to 15 mcgs depending upon the source)
(note: Estinyl estradiol -- as in birth control pills -- is generally said to be at least 3 to 5 times more potent than the other forms of estrogen used in HRT.)



PROGESTERONE/PROGESTIN

Type
Cyclical Dosage (the first number)
Continuous Dosage (the second number)

Medroxyprogesterone acetate (Provera) 5 mg 2.5 mg

Micronized progesterone (Prometrium) 200 mg 100 mg
Norethindron acetate (Aygestin) 5 mg 2.5 mg
Norethindrone (Micronor) .7 mg .35 mg
Progesterone gel (Prochieve 4%) every other day for 12 days (delivers 45 mg of progesterone per application) 2 times weekly